1921 Fixture
From Blueseum - History of the Carlton Football Club
| Round | Opponent | Venue | Date | Home / Away | Result |
| 1 | Richmond | Punt Road Oval | Saturday 7 May | Away | Won by 9 points |
| 2 | Bye | N/A | Saturday 14 May | N/A | N/A |
| 3 | St Kilda | Princes Park | Saturday 21 May | Home | Won by 23 points |
| 4 | Fitzroy | Princes Park | Saturday 28 May | Home | Drawn Match |
| 5 | Sth Melbourne | Lakeside Oval | Saturday 4 June | Away | Drawn Match |
| 6 | Essendon | East Melbourne Cricket Ground | Saturday 11 June | Away | Won by 57 points |
| 7 | Geelong | Princes Park | Saturday 18 June | Home | Won by 20 points |
| 8 | Melbourne | MCG | Saturday 25 June | Away | Won by 7 points |
| 9 | Collingwood | Princes Park | Saturday 2 July | Home | Won by 24 points |
| 10 | Richmond | Princes Park | Saturday 9 July | Home | Won by 51 points |
| 11 | Bye | N/A | Saturday 16 July | N/A | N/A |
| 12 | St Kilda | Junction Oval | Saturday 23 July | Away | Won by 98 points |
| 13 | Fitzroy | Brunswick Street Oval | Saturday 30 July | Away | Lost by 15 points |
| 14 | Sth Melbourne | Princes Park | Saturday 20 August | Home | Won by 25 points |
| 15 | Essendon | Princes Park | Saturday 27 August | Home | Won by 8 points |
| 16 | Geelong | Corio Oval | Saturday 3 September | Away | Won by 16 points |
| 17 | Melbourne | Princes Park | Saturday 10 September | Home | Won by 24 points |
| 18 | Collingwood | Victoria Park | Saturday 17 September | Away | Won by 27 points |
| SF | Collingwood | MCG | Saturday 1 October | Home | Won by 13 points |
| PF | Richmond | MCG | Saturday 8 October | Home | Lost by 8 points |
| GF | Richmond | MCG | Saturday 15 October | Away | Lost by 4 points |
